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SESSION CONTENT PLAN ABSTRACTS OF THE TWO RESEARCH PAPERS TO BE PRESENTED
A DIAGNOSTIC SCALE FOR AUTISM AND ASPERGER'S DISORDER IN ADULTS
OBJECTIVE: Development of a self-administered scale assisting clinicians in diagnosing adults with Autism and Asperger's Disorder. METHODS: A new 78 item self scoring scale based on DSM IV-TR-TR and ICD-10 criteria was administered to 17 Autistic and 20 Asperger's Disorder patients, 41 comparison subjects without a DSM IV-TR disorder, and 14 with another DSM IV-TR Axis I disorder. RESULTS: The Autistic and Asperger's groups scored significantly higher than comparison groups. Scores did not overlap and internal Sensitivity, specificity and content validity was perfect (no false positives, no false negatives). Cronbach Alpha coefficients of internal consistency of three subscales were satisfactory. Gender and Age and diagnostic categories were not significantly associated factors. CONCLUSIONS: This highly sensitive and specific scale is a useful clinical tool that can assist in the differential diagnosis of Autism and Asperger's disorder in adults. It can be administered and scored in less than an hour.
CLINICAL EVIDCE THAT ASPERGER'S DISORDER IS A MILD FORM OF AUTISM OBJECTIVE: To test the hypothesis that Asperger's Disorder is a mild form of autism, METHOD a 78-item scale was administered to 17adults with autism and 20 with Asperger's Disorder. RESULTS; 1) The mean number of symptoms scored present now and when I was young, only present now, and only present when I was young was not significantly different between the subject groups. 2) Asperger's Disorder subjects had the same symptoms as the autistic subjects, but answered significantly more often these (symptoms) were never true, indicating that they have a milder clinical course. CONCLUSIONS The data support hypothesis that Asperger's Disorder is a mild form of Autism and the corollary hypothesis that they share a common developmental neuropathology. Therefore, it appears reasonable that Asperger's Disorder and Autism be incorporated into one diagnostic category such as, Autism Spectrum Disorder, (severe, moderate, Asperger's type).
Learning Objectives:
Content Area: Medicine and Research
Riva Ariella Ritvo, PHD
Clinical Instructor
Yale university, Yale Child Study Center
Edward R. Ritvo, MD
PROFESSOR EMERITUS, UCLA MEDICAL SCHOOL
UCLA MEDICAL SCHOOL
Max Joseph Ritvo, Co-Author-scientific, journal
Research Associate
The Ritvo Clinic